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UNC0646

Product Specifications

CAS Number

1320288-17-2

Target

Histone Methyltransferase

Related Pathways

Chromatin/Epigenetic

Purity

>99.99%

Bioactivity

UNC0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases G9a and GLP (IC50s: 6 nM/15 nM for G9a/GLP) . UNC0646 (UNC 0646) potently blocks G9a/GLP methyltransferase activity in cells (IC50: 10 nM in MCF7 cells) and exhibits low cellular toxicity (EC50: 4.7 μM in MCF7 cells) .

Smiles

COc1cc2c(NC3CCN(CC3)C3CCCCC3)nc(nc2cc1OCCCN1CCCCC1)N1CCCN(CC1)C(C)C

Molecular Formula

C36H59N7O2

Molecular Weight

621.9

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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