UNC0646
Product Specifications
CAS Number
1320288-17-2
Target
Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Purity
>99.99%
Bioactivity
UNC0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases G9a and GLP (IC50s: 6 nM/15 nM for G9a/GLP) . UNC0646 (UNC 0646) potently blocks G9a/GLP methyltransferase activity in cells (IC50: 10 nM in MCF7 cells) and exhibits low cellular toxicity (EC50: 4.7 μM in MCF7 cells) .
Smiles
COc1cc2c(NC3CCN(CC3)C3CCCCC3)nc(nc2cc1OCCCN1CCCCC1)N1CCCN(CC1)C(C)C
Molecular Formula
C36H59N7O2
Molecular Weight
621.9
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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