NVP-CGM097

1313363-54-0

E1/E2/E3 Enzyme|||Mdm2|||MDM-2/p53

Apoptosis|||Ubiquitination

0.9892

NVP-CGM097 (CGM097) is an effective and specific MDM2 inhibitor (IC50: 1.7 nM for hMDM2) .

COc1cc2CC(=O)N([C@@H](c3ccc(Cl)cc3)c2cc1OC(C)C)c1ccc(cc1)N(C)C[C@H]1CC[C@@H](CC1)N1CCN(C)C(=O)C1

C38H47ClN4O4

659.26

Cool pack

-20°C