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Mavorixafor

Product Specifications

CAS Number

558447-26-0

Target

CXCR, HIV Protease

Related Pathways

Immunology/Inflammation, Proteases/Proteasome, GPCR/G Protein, Autophagy, Microbiology/Virology

Purity

0.9856

Bioactivity

Mavorixafor (AMD-070) is an effective and selective antagonist of CXCR4, with an IC50 value of 13 nM against CXCR4 125I-SDF binding. Mavorixafor inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells (IC50 = 1 nM) and PBMCs (IC50 = 9 nM) .

Smiles

N(CC=1NC=2C(N1)=CC=CC2)(CCCCN)[C@@H]3C=4C(CCC3)=CC=CN4

Molecular Formula

C21H27N5

Molecular Weight

349.47

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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