Mavorixafor
Product Specifications
CAS Number
558447-26-0
Target
CXCR|||HIV Protease
Related Pathways
Immunology/Inflammation|||Proteases/Proteasome|||GPCR/G Protein|||Autophagy|||Microbiology/Virology
Purity
0.9856
Bioactivity
Mavorixafor (AMD-070) is an effective and selective antagonist of CXCR4, with an IC50 value of 13 nM against CXCR4 125I-SDF binding. Mavorixafor inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells (IC50 = 1 nM) and PBMCs (IC50 = 9 nM) .
Smiles
N(CC=1NC=2C(N1)=CC=CC2)(CCCCN)[C@@H]3C=4C(CCC3)=CC=CN4
Molecular Formula
C21H27N5
Molecular Weight
349.47
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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