Naquotinib
Product Specifications
CAS Number
1448232-80-1
Target
EGFR
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling
Purity
0.9749
Bioactivity
Naquotinib (ASP8273) (ASP8273) is an orally available, mutant-selective and irreversible EGFR inhibitor; (IC50s: 8-33 nM and 230 nM toward EGFR mutants and EGFR.
Smiles
CCc1nc(C(N)=O)c(Nc2ccc(cc2)N2CCC(CC2)N2CCN(C)CC2)nc1O[C@@H]1CCN(C1)C(=O)C=C
Molecular Formula
C30H42N8O3
Molecular Weight
562.71
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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