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AVE 0991

Product Specifications

CAS Number

304462-19-9

Target

Others, RAAS

Related Pathways

Endocrinology/Hormones, Others

Purity

0.9973

Bioactivity

AVE 0991, a nonpeptide analog of angiotensin- (1-7) [Ang- (1-7) ], is an orally active Mas agonist with inhibitory effects on [125I]-Ang- (1-7) binding to bovine aortic endothelial cell membranes, and inhibits astrocyte-mediated neuroinflammation in Alzheimer's disease by enhancing autophagy.

Smiles

CCNC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2c(C=O)c(OC)nc2-c2ccccc2)cc1

Molecular Formula

C29H32N4O5S2

Molecular Weight

580.72

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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