AVE 0991
Product Specifications
CAS Number
304462-19-9
Target
Others, RAAS
Related Pathways
Endocrinology/Hormones, Others
Purity
0.9973
Bioactivity
AVE 0991, a nonpeptide analog of angiotensin- (1-7) [Ang- (1-7) ], is an orally active Mas agonist with inhibitory effects on [125I]-Ang- (1-7) binding to bovine aortic endothelial cell membranes, and inhibits astrocyte-mediated neuroinflammation in Alzheimer's disease by enhancing autophagy.
Smiles
CCNC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2c(C=O)c(OC)nc2-c2ccccc2)cc1
Molecular Formula
C29H32N4O5S2
Molecular Weight
580.72
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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