BI-882370
Product Specifications
CAS Number
1392429-79-6
Target
Raf
Related Pathways
MAPK
Purity
0.9907
Bioactivity
BI-882370 is a specific RAF kinase inhibitor. BI-882370 inhibits the oncogenic BRAFV600E-mutant, the WT BRAF and CRAF kinases (IC50s: 0.4, 0.8 and 0.6 nM) . BI-882370 also inhibits SRC family kinases.
Smiles
CCCS(=O)(=O)Nc1ccc(F)c(c1F)-n1cc(-c2cncnc2)c2nc(ccc12)N(C)C1CCN(CC)CC1
Molecular Formula
C28H33F2N7O2S
Molecular Weight
569.67
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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