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Rosiptor acetate

Product Specifications

CAS Number

782487-29-0

Target

Phosphatase, Others

Related Pathways

Others, Metabolism

Bioactivity

Rosiptor is a potent and selective SHIP1 activator. AQX-1125 inhibits Akt phosphorylation in SHIP1-proficient but not in SHIP1-deficient cells, reduces cytokine production in splenocytes, inhibits the activation of mast cells and inhibits human leukocyte chemotaxis. AQX-1125 suppresses leukocyte accumulation and inflammatory mediator release in rodent models of pulmonary inflammation and allergy.

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C(C)(O)=O.C[C@@]1([C@@]2([C@@H](CN)[C@]3([C@](C)(CC2)C(=C)CC3)[H])[H])[C@@H](CO)C[C@@H](O)CC1

Molecular Formula

C22H39NO4

Molecular Weight

381.55

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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