Rosiptor acetate
Product Specifications
CAS Number
782487-29-0
Target
Phosphatase, Others
Related Pathways
Others, Metabolism
Bioactivity
Rosiptor is a potent and selective SHIP1 activator. AQX-1125 inhibits Akt phosphorylation in SHIP1-proficient but not in SHIP1-deficient cells, reduces cytokine production in splenocytes, inhibits the activation of mast cells and inhibits human leukocyte chemotaxis. AQX-1125 suppresses leukocyte accumulation and inflammatory mediator release in rodent models of pulmonary inflammation and allergy.
Smiles
C(C)(O)=O.C[C@@]1([C@@]2([C@@H](CN)[C@]3([C@](C)(CC2)C(=C)CC3)[H])[H])[C@@H](CO)C[C@@H](O)CC1
Molecular Formula
C22H39NO4
Molecular Weight
381.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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