ASTX660
Product Specifications
CAS Number
1799328-86-1
Target
Apoptosis, IAP
Related Pathways
Apoptosis
Purity
0.9985
Bioactivity
Tolinapant (ASTX660) is an orally bioavailable cIAP1/2 and XIAP antagonist that induces expression of immunogenic cell death (ICD) markers in sensitive HNSCC cell lines in vitro.
Smiles
C[C@@H]1CN(CC(=O)N2CC(C)(C)c3nc(CO)c(Cc4ccc(F)cc4)cc23)[C@@H](CN2CCOC[C@H]2C)CN1
Molecular Formula
C30H42FN5O3
Molecular Weight
539.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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