Ningetinib
Product Specifications
CAS Number
1394820-69-9
Target
VEGFR, c-Met/HGFR, TAM Receptor
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis
Purity
0.9998
Bioactivity
Ningetinib (CT-053) (CT053PTSA) is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.
Smiles
Cc1c(C(=O)Nc2ccc(Oc3ccnc4cc(OCC(C)(C)O)ccc34)c(F)c2)c(=O)n(-c2ccccc2)n1C
Molecular Formula
C31H29FN4O5
Molecular Weight
556.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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