Brepocitinib
Product Specifications
CAS Number
1883299-62-4
Target
JAK, Tyrosine Kinases
Related Pathways
JAK/STAT signaling, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, Stem Cells, Angiogenesis
Purity
0.9982
Bioactivity
Brepocitinib (PF-06700841) is a potent dual JAK1/TYK2 inhibitor with IC50 values of 17 nM and 23 nM, respectively, and also inhibits JAK2 and JAK3 with IC50 values of 77 nM and 6.49 μM.
Smiles
C(=O)(N1C2CN(CC1CC2)C3=NC(NC=4C=NN(C)C4)=NC=C3)[C@H]5C(F)(F)C5
Molecular Formula
C18H21F2N7O
Molecular Weight
389.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS1437974-01 0.02 mg (E-Coli)
Recombinant Alkalilimnicola ehrlichei UDP-N-acetylenolpyruvoylglucosamine reductase (murB)
Sign In for Pricing
View Details MBS1437974-02 0.02 mg (Yeast)
Recombinant Alkalilimnicola ehrlichei UDP-N-acetylenolpyruvoylglucosamine reductase (murB)
Sign In for Pricing
View Details 
MBS1437974-03 0.1 mg (E-Coli)
Recombinant Alkalilimnicola ehrlichei UDP-N-acetylenolpyruvoylglucosamine reductase (murB)
Sign In for Pricing
View Details 
MBS1437974-04 0.1 mg (Yeast)
Recombinant Alkalilimnicola ehrlichei UDP-N-acetylenolpyruvoylglucosamine reductase (murB)
Sign In for Pricing
View Details 
MBS1437974-05 0.02 mg (Baculovirus)
Recombinant Alkalilimnicola ehrlichei UDP-N-acetylenolpyruvoylglucosamine reductase (murB)
Sign In for Pricing
View Details