Brepocitinib
Product Specifications
CAS Number
1883299-62-4
Target
JAK|||Tyrosine Kinases
Related Pathways
JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Chromatin/Epigenetic|||Stem Cells|||Angiogenesis
Purity
0.9982
Bioactivity
Brepocitinib (PF-06700841) is a potent dual JAK1/TYK2 inhibitor with IC50 values of 17 nM and 23 nM, respectively, and also inhibits JAK2 and JAK3 with IC50 values of 77 nM and 6.49 ?M.
Smiles
C(=O)(N1C2CN(CC1CC2)C3=NC(NC=4C=NN(C)C4)=NC=C3)[C@H]5C(F)(F)C5
Molecular Formula
C18H21F2N7O
Molecular Weight
389.4
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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