ThioLox
ThioLox is a competitive 15-lipoxygenase-1 (15-LOX-1) inhibitor with a Ki of 3.30 μM. ThioLox shows anti-inflammatory and neuroprotective properties[1].
Product Specifications
CAS Number
1202193-89-2
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Lipoxygenase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/thiolox.html
Purity
99.74
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=C(N)SC(C2=CC=CC=C2)=C1)NCCCC
Molecular Formula
C15H18N2OS
Molecular Weight
274.38
Precautions
H302, H315, H319
References & Citations
[1]Eleftheriadis N, et al. Design of a novel thiophene inhibitor of 15-lipoxygenase-1 with both anti-inflammatory and neuroprotective properties. Eur J Med Chem. 2016 Oct 21;122:786-801.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
HA610204 100 µg
Recombinant Mouse IgG1 Recombinant Mouse monoclonal Antibody
Sign In for Pricing
View Details 
LC401889 20 µg
Macrophage Inflammatory Protein 3 beta (CCL19) (NM_006274) Human Over-expression Lysate
Sign In for Pricing
View Details