PMX 53 acetate (219639-75-5 free base)
Product Specifications
CAS Number
852629-88-0
Target
Endogenous Metabolite, Complement System
Related Pathways
Metabolism, Immunology/Inflammation
Purity
0.9991
Bioactivity
PMX-53 is a potent and orally active CD88 (C5aR) antagonist (IC50: 20 nM) and inhibits C5a-induced neutrophil myeloperoxidase release and chemotaxis with IC50 values of 22 nM and 75 nM, respectively. PMX-53 is also an agonist of Mas-related gene 2 (MrgX2) .
Smiles
N=C(N)NCCC[C@@H]1NC([C@H](CC2=CNC3=C2C=CC=C3)NC([C@@H](CC4CCCCC4)NC([C@H]5N(C([C@H](CCCNC1=O)NC([C@H](CC6=CC=CC=C6)NC(C)=O)=O)=O)CCC5)=O)=O)=O.CC(O)=O
Molecular Formula
C49H69N11O9
Molecular Weight
956.16
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LV675413 1.0 µg DNA
IL4 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
Sign In for Pricing
View Details 
MBS6475768-01 0.1 mL
Fen1 (Flap Endonuclease 1, Flap Structure-specific Endonuclease 1, FEN-1, DNase IV, hFEN-1, Maturation Factor 1, MF1, RAD2) (FITC)
Sign In for Pricing
View Details MBS6475768-02 5x 0.1 mL
Fen1 (Flap Endonuclease 1, Flap Structure-specific Endonuclease 1, FEN-1, DNase IV, hFEN-1, Maturation Factor 1, MF1, RAD2) (FITC)
Sign In for Pricing
View Details orb1293443-01 25 assay
CD8a Mouse Monoclonal Antibody (Pacific Blue)
Sign In for Pricing
View Details