Cannflavin B
Cannflavin B is a flavonoid compound that can be isolated from Cannabis sativa L. Cannflavin B is inhibitors of PGE2 release (IC50: 0.7 μM), mPGES-1 (IC50: 3.7 μM), and 5-lipoxygenase. Cannflavin B has multiple activities such as anti-inflammatory, antioxidant, anti-glycation, anti-ferroptosis, anti-tumor, and anti-Leishmania (IC50: 14 μM) . Cannflavin B can also inhibit the TrkB-BDNF signaling pathway[1][2][3][4].
Product Specifications
CAS Number
76735-58-5
Product Name Alternative
Canniflavone
UNSPSC
12352005
Target
Akt; Ferroptosis; Lipoxygenase; mTOR; p38 MAPK; Parasite; PGE synthase; Trk Receptor
Type
Natural Products
Related Pathways
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cannflavin-b.html
Purity
98.36
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1C=C(C2=CC(OC)=C(O)C=C2)OC3=CC(O)=C(C/C=C(C)\C)C(O)=C13
Molecular Formula
C21H20O6
Molecular Weight
368.38
References & Citations
Cannabis sativa[1]
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
5-LOX; TrkB
Available Sizes
Frequently Asked Questions
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