Rapalink-1
Product Specifications
CAS Number
1887095-82-0
Target
Autophagy|||mTOR
Related Pathways
PI3K/Akt/mTOR signaling|||Autophagy
Bioactivity
Rapalink-1 is a brain-permeable mTOR inhibitor that inhibits oxidative stress-induced DNA damage and senescence in ethanol-exposed endothelial cells, and inhibits the mTORC1-4E-BP1 pathway in mice.Rapalink-1 is used for the study of prostate cancer due to its anticancer activity.
Smiles
NC1=C2C(=NN(CCCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCN3C=C(COCCO[C@H]4[C@H](OC)C[C@H](C[C@@H](C)[C@]5(OC(=O)[C@]6(N(C(=O)C(=O)[C@]7(O)O[C@@](CC[C@H]7C)(C[C@H](OC)\C(\C)=C\C=C\C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(/C)=C\[C@@H](C)C(=O)C5)[H])CCCC6)[H])[H])CC4)N=N3)=O)C2=NC=N1)C=8C=C9C(=CC8)OC(N)=N9
Molecular Formula
C91H138N12O24
Molecular Weight
1784.14
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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