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Endostatin (84-114) -NH2 (JKC367)

Product Specifications

Target

Others

Related Pathways

Others

Bioactivity

Endostatin is a potent inhibitor of primary tumor growth and endothelial cell proliferation and migration. Recombinant endostatin potently inhibited angiogenesis, maintains metastases at a low level, and suppressed tumors, a reduction of over 150-fold. Endostatin showed no toxicity to mice, no evidence of drug resistance, and no regrowth of tumors.

Smiles

O=C(NCC(=O)N[C@](C)([H])C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@]([H])(C(=O)N[C@@]([H])(C/C1=C/C=CC=C1)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(C/C2=C/C=CC=C2)C(=O)N[C@@]([H])(CC(=O)O)C(=O)NCC(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@]([H])(C(=O)N[C@@]([H])(CC(C)(C)[H])C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@]([H])(CC=3N=CNC=3)C(=O)N4CCC[C@]4([H])C(=O)N[C@]([H])(C(=O)N[C@@]([H])(C/C5=C/NC=6C=CC=CC5=6)C(=O)N7CCC[C@@]7([H])C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CO)C(=O)N[C@]([H])(C(=O)N[C@@]([H])(C/C9=C/NC=8C=CC=CC=89)C(=O)N[C@@]([H])(C/C%10=C/NC=N%10)C(=O)NCC(=O)N[C@]([H])(CO)C(=O)N[C@]([H])(CC(O)=O)C(=O)N%11CCC[C@@]%11([H])C(=O)N[C@@]([H])(CC(N)=O)C(N)=O)C(C)(C)[H])[C@](C)(O)[H])C(C)(C)[H])[C@](C)([H])CC)[C@@]%12([H])NCCC%12

Molecular Formula

C161H236N48O43

Molecular Weight

3531.9

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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