Coagulation factor II (thrombin) B chain fragment [Homo sapiens]

Thrombin is a "trypsin-like" serine protease that is encoded by the F2 gene in humans. Thrombin is produced by the enzymatic cleavage of two sites on prothrombin by activated Factor X (Xa) . Thrombin in turn acts as a serine protease that converts soluble fibrinogen into insoluble strands of fibrin. Thrombin is also active in the catalysis of many other coagulation-related reactions.

N[C@@]([H])(CCCCN)C(=O)N1CCC[C@@]1([H])C(=O)N[C@]([H])(C(=O)N[C@](C)([H])C(=O)N[C@]([H])(C/C2=C/C=CC=C2)C(=O)N[C@]([H])(CO)C(=O)N[C@@]([H])(CC(O)=O)C(=O)N[C@]([H])(C/C3=C/C=C(/O)C=C3)C(=O)N[C@@]([H])(C(=O)N[C@]([H])(C/C4=C/N=CN4)C(=O)N5CCC[C@@]5([H])C(=O)N[C@]([H])(C(=O)N[C@]([H])(C[S])C(=O)N[C@@]([H])(CC(C)(C)[H])C(=O)N6CCC[C@]6([H])C(=O)N[C@]([H])(CC(O)=O)C(=O)N[C@]([H])(CCCNC(N)=N)C(=O)O)C(C)(C)[H])[C@@](C)([H])CC)C(C)(C)[H]