APTSTAT3-9R
Product Specifications
Target
Others, STAT
Related Pathways
Stem Cells, JAK/STAT signaling, Others
Bioactivity
APTSTAT3-9R-9R is a STAT3 inhibitor (Ki: 231 nmol/L) . STAT3 has been reported to promote the proliferation, survival, metastasis, immune escape, as well as drug resistance of cancer cells, making it a promising target for various diseases. However, though multiple STAT3 inhibitors and its regulatory or effector pathway elements have been identified, bioactive agents are limited.
Smiles
NC(CC1=CNC=N1)C(NC([H])C(NC(CC2=CC=CC=C2)C(NC(CCC(N)=O)C(NC(CC3=CNC4=C3C=CC=C4)C(N5C(C(NC([H])C(NC(CO)C(NC(CC6=CNC7=C6C=CC=C7)C(NC([C@@H](C)O)C(NC(CC8=CNC9=C8C=CC=C9)C(NC(CCC(O)=O)C(NC(CC(N)=O)C(NC([H])C(NC(CCCCN)C(NC(CC%10=CNC%11=C%10C=CC=C%11)C(NC([C@@H
Molecular Formula
C223H330N80O51
Molecular Weight
4947.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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