E3 Ligase Ligand-linker Conjugate 147
Product Specifications
UNSPSC Description
E3 Ligase Ligand-linker Conjugate 147 is a conjugate of E3 ligase ligand and PROTAC Linker, which can be used to synthesize BRD9 Degrader-1 (HY-156401) (Compound 13-7)[1]. E3 Ligase Ligand-linker Conjugate 147 is composed of the E3 ligase ligand BRD9 ligand-7 (HY-168695) and the PROTA linker 2-((1R,5S,6s)-3-Azabicyclo[3.1.0]hexan-6-yl)ethan-1-ol (HY-W763939).
Target Antigen
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
cancer
Assay Protocol
https://www.medchemexpress.com/e3-ligase-ligand-linker-conjugate-147.html
Smiles
[H][C@]12CNC[C@@]1([H])[C@@H]2CCOC3=CC(C4=C(C)N=CS4)=CC=C3CNC([C@H]5N(C([C@H](C(C)(C)C)NC(C6(CC6)F)=O)=O)C[C@@H](C5)O)=O
Molecular Weight
641.80
References & Citations
[1]Liu S, et al. Rational Screening for Cooperativity in Small-Molecule Inducers of Protein-Protein Associations. J Am Chem Soc. 2023 Oct 25;145(42):23281-23291.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-168694/E3-Ligase-Ligand-linker-Conjugate-147-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-168694/
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS2169301-01 0.1 mL
FITC-Linked Monoclonal Antibody to Glutathione S Transferase Alpha 1 (GSTa1)
Ask
View Details MBS2169301-02 0.2 mL
FITC-Linked Monoclonal Antibody to Glutathione S Transferase Alpha 1 (GSTa1)
Ask
View Details