LSKL TFA
Product Specifications
CAS Number
2828433-17-4
Target
TGF-beta/Smad
Related Pathways
Stem Cells
Purity
0.9933
Bioactivity
LSKL TFA (H-Leu-Ser-Lys-Leu-NH2 TFA) is a LAP-TGFβ derivative and a TGF-β1 antagonist that can cross the blood-brain barrier, inhibits the binding of TSP-1 to LAP and reduces renal interstitial fibrosis and liver fibrosis, inhibits subarachnoid fibrosis by inhibiting TSP-1-mediated TGF-β1 activity, prevents the occurrence of chronic hydrocephalus and improves long-term neurocognitive deficits after subarachnoid hemorrhage.
Smiles
O=C(O)C(F)(F)F.CC(C)C[C@@H](C(N)=O)NC([C@H](CCCCN)NC([C@H](CO)NC([C@@H](N)CC(C)C)=O)=O)=O
Molecular Formula
C23H43F3N6O7
Molecular Weight
572.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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