Balixafortide TFA (1051366-32-5 free base)
Product Specifications
Target
CXCR
Related Pathways
GPCR/G Protein, Autophagy, Immunology/Inflammation
Bioactivity
Balixafortide TFA (POL6326 TFA) is a selective, well-tolerated peptidic CXCR4 antagonist (IC50 < 10 nM) . It shows 1000-fold selective for CXCR4 than a large panel of receptors including CXCR7. Balixafortide TFA blocks β-arrestin recruitment and calcium flux (IC50s < 10 nM) .
Molecular Formula
C82H113N22F3O23S2
Molecular Weight
1896.05
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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