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AMY-101

Product Specifications

CAS Number

1427001-89-5

Target

SARS-CoV|||Others|||Complement System

Related Pathways

Microbiology/Virology|||Immunology/Inflammation|||Others

Bioactivity

AMY-101 is a peptidic inhibitor of the central complement component C3 (KD: 0.5 nM) . AMY-101 shows a favorable anti-inflammatory activity in models with COVID-19 severe pneumonia with systemic hyper inflammation.

Smiles

CC[C@H](C)[C@H](NC(=O)[C@H](N)Cc1ccc(O)cc1)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](C)NC(=O)CN(C)C(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc2cn(C)c3ccccc23)NC(=O)[C@@H](NC1=O)C(C)C)C(=O)N(C)[C@@H]([C@@H](C)CC)C(N)=O

Molecular Formula

C83H117N23O18S2

Molecular Weight

1789.11

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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