[Ala92]-p16 (84-103)
Product Specifications
CAS Number
189064-08-2
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Bioactivity
Peptide derived from the tumor suppressor protein p16; inhibits cyclin-dependent kinase-4 (cdk4) /cyclin D1 (IC50 ~ 1.5 μM) and binds to cdk6.
Smiles
[C@H](CC1=CN=CN1)(C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)C)=O)=O)C)=O)CCCNC(=N)N)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=CC=C2)NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC(O)=O)N)=O)C)=O)C)=O)CCCNC(=N)N)=O)CCC(O)=O)=O)=O)=O)CC(C)C)=O)C)=O)[C@@H](C)O)=O)CC(C)C)=O)C(C)C)=O)C(C)C)=O)CC(C)C)=O
Molecular Formula
C93H155N31O26
Molecular Weight
2123.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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