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SAHM1

Product Specifications

CAS Number

2050906-89-1

Target

Gamma-secretase

Related Pathways

Neuroscience, Proteases/Proteasome, Stem Cells

Bioactivity

Notch pathway inhibitor - stabilized hydrocarbon-stapled alpha helical peptide. Targets the protein-protein interface and prevents Notch complex assembly.

Smiles

[C@H](CC1=CN=CN1)(C(N[C@@H](CC2=CN=CN2)C(N[C@H](C(N[C@@H]([C@@H](C)O)C(O)=O)=O)CO)=O)=O)NC(=O)[C@@]3(C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CS)NC(=O)[C@H](CC(C)C)NC(=O)[C@@](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CCNC(C)=O)=O)CCC(O)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)[C@H](CC)C)=O)(C)CCCC=CCCC3

Molecular Formula

C94H162N36O23S

Molecular Weight

2196.58

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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