SAHM1

Notch pathway inhibitor - stabilized hydrocarbon-stapled alpha helical peptide. Targets the protein-protein interface and prevents Notch complex assembly.

[C@H](CC1=CN=CN1)(C(N[C@@H](CC2=CN=CN2)C(N[C@H](C(N[C@@H]([C@@H](C)O)C(O)=O)=O)CO)=O)=O)NC(=O)[C@@]3(C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CS)NC(=O)[C@H](CC(C)C)NC(=O)[C@@](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CCNC(C)=O)=O)CCC(O)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)[C@H](CC)C)=O)(C)CCCC=CCCC3