TAT-Gap19 acetate

Product Specifications

Target

Gap Junction Protein

Related Pathways

Cytoskeletal Signaling

Purity

0.9974

Bioactivity

TAT-Gap19 acetate is a specific inhibitor of connexin43 hemichannel (Cx43 HC) . TAT-Gap19 acetate traverses the blood-brain barrier and alleviates liver fibrosis in mice. TAT-Gap19 acetate does not inhibit the corresponding Cx43 GJCs.

Smiles

CC[C@H](C)[C@@H](C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](Cc1ccccc1)C(N[C@@H](CCCCN)C(O)=O)=O)=O)=O)=O)NC([C@H](CCC(O)=O)NC([C@H]([C@@H](C)CC)NC([C@H](CCC(N)=O)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC(CNC([C@H](Cc(cc1)ccc1O)N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O