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TAT-Gap19

Product Specifications

CAS Number

1507930-54-2

Target

Gap Junction Protein

Related Pathways

Cytoskeletal Signaling

Bioactivity

Cx43 hemichannel blocker (IC50 ~7 ?M) . No significant affinity for gap junctions or Panx1 channels. N-terminal transactivator of transcription (TAT) motif promotes membrane permeability and increases inhibitory effect of Gap19. Active in vivo. Brain penetrant.

Smiles

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