Urantide acetate (669089-53-6 free base)

Product Specifications

CAS Number

9007-83-4

Target

Neurotensin Receptor

Related Pathways

GPCR/G Protein

Purity

0.9922

Bioactivity

Urantide acetate is a selective and competitive urotensin-II (UT) receptor antagonist (pKB = 8.3) . Blocks hU-II induced contractions in thoracic aorta ex vivo. Exhibits no effect on noradrenaline or endothelin 1-induced contraction or on acetylcholine-induced relaxation. Behaves as a partial agonist in a calcium mobilization assay (in CHO cells expressing hUT receptors) .

Smiles

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