Echistatin
Product Specifications
CAS Number
154303-05-6
Target
Integrin
Related Pathways
Cytoskeletal Signaling
Bioactivity
Potent irreversible ?V?3 integrin antagonist (Ki = 0.27 nM) . Disrupts attachment of osteoclasts to bone and inhibits bone reabsorption (IC50 = 0.1 nM) . Prevents ADP-induced platelet aggregation via inhibition of glycoprotein IIb/IIIa (GpIIb/IIIa, ?IIb?3) receptors (IC50 = 30 nM) in vitro.
Molecular Formula
C217H341N71O74S9
Molecular Weight
5417.1
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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