Apelin-36 (rat, mouse)
Product Specifications
CAS Number
230299-95-3
Target
Apelin receptor, HIV Protease
Related Pathways
Microbiology/Virology, Proteases/Proteasome, GPCR/G Protein
Bioactivity
Endogenous APJ receptor agonist that is secreted by adipocytes. Binds with high affinity to APJ receptors (IC50 = 5.4 nM) and potently inhibits cAMP production in vitro (EC50 = 0.52 nM) . Involved in regulation of cardiovascular function, fluid homeostasis and feeding. Blocks entry of some HIV-1 and HIV-2 strains into NP-2/CD4 cells expressing APJ.
Molecular Formula
C185H304N68O43S
Molecular Weight
4200.93
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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