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Apelin-36 (human)

Product Specifications

CAS Number

252642-12-9

Target

Apelin receptor, HIV Protease

Related Pathways

Microbiology/Virology, Proteases/Proteasome, GPCR/G Protein

Bioactivity

Endogenous APJ receptor agonist (EC50 = 20 nM) that is secreted by adipocytes. Binds with high affinity to human APJ receptors expressed in HEK 293 cells (pIC50= 8.61) . Involved in regulation of cardiovascular function, fluid homeostasis and feeding. Blocks entry of some HIV-1 and HIV-2 strains into NP-2/CD4 cells expressing APJ.

Molecular Formula

C184H297N69O43S

Molecular Weight

4195.87

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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