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APETx2

Product Specifications

CAS Number

713544-47-9

Target

Sodium Channel

Related Pathways

Membrane transporter/Ion channel

Bioactivity

Acid-sensing ion channel 3 (ASIC3) channel blocker (IC50 values are 63 and 175 nM for homomeric rat and human ASIC3 channels) . Also inhibits NaV1.8 and NaV1.2 channels (IC50 values are 55 and 114 nM respectively) . Demonstrates analgesic properties against acid-induced and inflammatory pain.

Molecular Formula

C196H280N54O61S6

Molecular Weight

4561.06

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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