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Bay 55-9837

Product Specifications

CAS Number

463930-25-8

Target

Glucagon Receptor

Related Pathways

GPCR/G Protein

Bioactivity

Selective VPAC2 receptor agonist (EC50 values are 0.4, 100 and >1000 nM for VPAC2, VPAC1 and PAC1, respectively in a cAMP accumulation assay; IC50 values are 60, 8700 and >10000 nM for VPAC2, VPAC1 and PAC1, respectively in a competition binding assay) . Stimulates glucose-dependent insulin secretion in isolated human pancreatic islets. Reduces HIV-1 viral replication and shows cooperative effects when given in conjunction with VPAC1 agonists.

Molecular Formula

C167H270N52O46

Molecular Weight

3742.29

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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