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α-Conotoxin MII acetate

Product Specifications

Target

AChR

Related Pathways

Neuroscience

Purity

0.9779

Bioactivity

α-Conotoxin MII acetate is a 16-amino acid peptide from the venom of the marine snail Conus magus. α-Conotoxin MII acetate potently blocks nicotinic acetylcholine receptors composed of α3β2 subunits, with an IC50 of 0.5 nM. α-Conotoxin MII acetate potently blocks β3-containing neuronal nicotinic acetylcholine receptors.

Smiles

CC(O)=O.[H][C@@]12CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@]1([H])CSSC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)[C@H](CSSC[C@H](NC(=O)CN)C(=O)N1)NC(=O)[C@@H](NC2=O)C(C)C)C(N)=O

Molecular Formula

C69H107N23O24S4

Molecular Weight

1770.99

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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