CTAP (TFA) (103429-32-9 free base)

Product Specifications

Target

Opioid Receptor

Related Pathways

Neuroscience|||Endocrinology/Hormones|||GPCR/G Protein

Purity

0.9962

Bioactivity

CTAP (TFA) (103429-32-9 free base) is a potent, highly selective, and brain-penetrant antagonist of the ?-opioid receptor with IC50 of 3.5 nM. It displays over 1200-fold selectivity over ? opioid (IC50=4500 nM) and somatostatin receptors. CTAP (TFA? (103429-32-9 free base) can be used for the study of L-DOPA-induced dyskinesia (LID)

Smiles

CC(O)C1C(NC(C(NC(C(N)=O)C(O)C)=O)C(C)(C)SSCC(NC(C(N)CC2=CC=CC=C2)=O)C(NC(CC3=CC=C(O)C=C3)C(NC(CC4=CNC5=CC=CC=C54)C(NC(CCC/N=C(N)\N)C(N1)=O)=O)=O)=O)=O.O=C(O)C(F)(F)F