CRSP-1
Product Specifications
CAS Number
697327-12-1
Target
CGRP Receptor
Related Pathways
Neuroscience, GPCR/G Protein
Bioactivity
Endogenous central calcitonin (CT) receptor agonist that stimulates cAMP formation at a potency 350-fold greater than CT (ED50 values are 0.2 and 71 nM respectively) . Displays no activity at calcitonin-gene related peptide (CGRP) and adrenomedullin receptors. Inhibits formation of multinuclear osteoclasts with similar efficacy to CT in vitro. Suppresses food intake and increases body temperature in free-feeding rats, and significantly decreases plasma calcium levels in vivo.
Molecular Formula
C175H294N54O49S5
Molecular Weight
4098.88
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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