CH 275

Potent somatostatin receptor 1 (sst1) agonist; displays selectivity for sst1 (IC50 values are 30.9 nM, 345 nM, > 1 ?M, > 10 ?M and > 10?M for human sst1, sst3, sst4, sst2 and sst5 respectively) . Attenuates somatostatin release in the rat nucleus accumbens.

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