C 21
Product Specifications
CAS Number
1229236-78-5
Target
Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Bioactivity
Selective protein arginine methyltransferase 1 (PRMT1) inhibitor (IC50 = 1.8 μM) . Exhibits five-fold selectivity for PRMT1 over PRMT6 and >250-fold selectivity over PRMT3 and CARM1.
Smiles
[C@H](CC1=CN=CN1)(C(N[C@H](C(N[C@H](C(N[C@@H]([C@H](C)C)C(O)=O)=O)CCCCN)=O)CCCNC(=N)N)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC(CNC([C@@H](NC(CNC([C@@H](NC(CNC([C@@H](NC(CNC(CNC([C@@H](NC(CNC([C@@H](NC(CNC([C@@H](NC(C)=O)CO)=O)=O)CCCNC(CCl)=N)=O)=O)CCCCN)=O)=O)=O)CCCCN)=O)=O)CC(C)C)=O)=O)CCCCN)=O)=O)=O)C)=O)CCCCN)=O)CCCNC(=N)N)=O
Molecular Formula
C90H161ClN36O24
Molecular Weight
2166.94
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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