FSL-1

Product Specifications

CAS Number

322455-70-9

Target

TLR|||Antibiotic

Related Pathways

Microbiology/Virology|||Immunology/Inflammation

Bioactivity

TLR2/6 agonist (also a putative TLR10 ligand) . Activates NF-?B. Induces pro-inflammatory cytokines including IL-8, IL-1?, CCL20 and TNF-? in vitro. Synergizes with IFN? to induce CXCL10 release from melanoma cells.

Smiles

C([C@H](CC1=CN=CN1)NC([C@@H](NC(=O)[C@H]2N(C([C@@H](NC(CNC([C@H](CSCC(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)N)=O)=O)CC(O)=O)=O)CCC2)CCCCN)=O)(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(O)=O)=O)CO)=O)CCCCN)=O)CCC3