GR 64349
Product Specifications
CAS Number
137593-52-3
Target
Neurokinin receptor
Related Pathways
Neuroscience, GPCR/G Protein
Bioactivity
Potent and selective tachykinin NK2 receptor agonist (EC50 = 3.7 nM in rat colon) . Displays > 1000- and > 300-fold selectivity over NK1 and NK3 receptors respectively. Active in vivo.
Smiles
CSCC[C@H](NC(=O)[C@H](CC(C)C)N1CC[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](N)CCCCN)C(C)C)C1=O)C(N)=O
Molecular Formula
C42H68N10O11S
Molecular Weight
921.12
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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