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[Pro3]-GIP (Mouse)

Product Specifications

Target

IGF-1R

Related Pathways

Tyrosine Kinase/Adaptors

Bioactivity

GIP receptor antagonist (IC50 = 2.6μM) . Inhibits GIP-stimulated insulin release from pancreatic β cells in vitro. In ob/ob mice, blocks the effects of GIP on insulin release and plasma glucose levels. Also improves intraperitoneal glucose tolerance, insulin sensitivity, and glucose response to feeding in ob/ob mice.

Molecular Formula

C225H342N62O64S

Molecular Weight

4971.62

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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