[Pro3]-GIP (Mouse)
Product Specifications
Target
IGF-1R
Related Pathways
Tyrosine Kinase/Adaptors
Bioactivity
GIP receptor antagonist (IC50 = 2.6?M) . Inhibits GIP-stimulated insulin release from pancreatic ? cells in vitro. In ob/ob mice, blocks the effects of GIP on insulin release and plasma glucose levels. Also improves intraperitoneal glucose tolerance, insulin sensitivity, and glucose response to feeding in ob/ob mice.
Molecular Formula
C225H342N62O64S
Molecular Weight
4971.62
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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