[Ala17]-MCH
Product Specifications
CAS Number
359784-84-2
Target
GPCR, Melanin-concentrating Hormone Receptor (MCHR)
Related Pathways
Endocrinology/Hormones, GPCR/G Protein
Bioactivity
Potent melanin-concentrating hormone (MCH) receptor agonist (EC50 values are 17 and 54 nM at MCH1 and MCH2 receptors respectively) . Displays some selectivity towards MCH1 over MCH2 (Ki values are 0.16 and 34 nM respectively) .
Smiles
O=C1N2C(C(=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]([C@H](C)C)C(O)=O)=O)CCC(N)=O)=O)C)=O)CSSC[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=CC=C3)NC([C@H](CC(O)=O)N)=O)=O)CC(O)=O)=O)CCSC)=O)CC(C)C)=O)CCCNC(=N)N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H]([C@@H](C)C)C(=O)N[C@@H](CC4=CC=C(O)C=C4)C(=O)N[C@H]1CCCNC(=N)N)(CCC2)[H]
Molecular Formula
C97H155N29O26S4
Molecular Weight
2271.71
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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