Parstatin (mouse)
Product Specifications
CAS Number
1065756-01-5
Target
Protease-activated Receptor
Related Pathways
GPCR/G Protein
Bioactivity
Cell-permeable peptide cleaved from protease-activated receptor 1 (PAR1) upon receptor activation. Attenuates endothelial cell migration and proliferation (IC50 ~ 20 μM), and induces cell cycle arrest. Promotes activation of caspase-3 and exhibits pro-apoptotic activity in vitro. Inhibits angiogenesis and exhibits cardioprotective activity in vivo.
Molecular Formula
C189H326N58O57S3
Molecular Weight
4419.19
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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