Parstatin (human)
Product Specifications
CAS Number
1065755-99-8
Target
Protease-activated Receptor
Related Pathways
GPCR/G Protein
Bioactivity
Cell-permeable peptide cleaved from protease-activated receptor 1 (PAR1) upon receptor activation. Attenuates endothelial cell migration and proliferation (IC50 ~ 3 μM), and induces cell cycle arrest. Promotes activation of caspase-3 and exhibits pro-apoptotic activity in vitro. Inhibits angiogenesis and exhibits cardioprotective activity in vivo.
Molecular Formula
C191H330N64O53S3
Molecular Weight
4467.29
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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