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PL-017

Product Specifications

CAS Number

83397-56-2

Target

Opioid Receptor

Related Pathways

GPCR/G Protein|||Neuroscience|||Endocrinology/Hormones

Bioactivity

Selective ? opioid receptor agonist (IC50 values are 5.5 and > 10000 nM for inhibition of 125I-FK 33,824 and 125I-DADLE binding to ? and ? sites respectively) . Produces naloxone-reversible analgesia, catalepsy and hyperthermia following central administration in rats in vivo.

Smiles

C(N([C@H](C(=O)N1[C@@H](C(N)=O)CCC1)CC2=CC=CC=C2)C)(=O)[C@H]3N(C([C@H](CC4=CC=C(O)C=C4)N)=O)CCC3

Molecular Formula

C29H37N5O5

Molecular Weight

535.64

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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